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Ecthyma GangrenosumAn Unusual Cutaneous Manifestation of the Head and Neck
Etai Funk, MD;
Doina Ivan, MD;
Ann M. Gillenwater, MD
Arch Otolaryngol Head Neck Surg. 2009;135(8):818-820.
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INTRODUCTION
Ecthyma gangrenosum (EG) is a recognized cutaneous infection commonly associated with Pseudomonas aeruginosa bacteremia. It typically occurs in patients who are septic and severely immunocompromised. Clinical presentation characteristically begins as an erythematous or hemorrhagic vesicle or bulla, which evolves into a necrotic ulcer with eschar and surrounding erythema. This was first described in association with Pseudomonas septicemia by Barker in 1897 and was later given the name "ecthyma gangrenosum" by Hitschmann and Kreibich.1
REPORT OF A CASE
A 28-year-old white man with a medical history of acute myelogenous leukemia (AML), who had undergone a stem cell transplantation, was readmitted to MD Anderson Cancer Center, Houston, Texas, for a fever of 39.9°C and fatigue approximately 1 month after transplantation. A workup for fever revealed P aeruginosa bacteremia. He began therapy with ceftazidime and ciprofloxacin as directed by the infectious disease service. At this point, the . . . [Full Text of this Article]
COMMENT
AUTHOR INFORMATION
Author Affiliations: Bobby R. Alford Department of Otolaryngology–Head and Neck Surgery, Baylor College of Medicine, Houston, Texas (Dr Funk); and Departments of Pathology (Dr Ivan) and Head and Neck Surgery (Dr Gillenwater), The University of Texas M. D. Anderson Cancer Center, Houston.
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